Doxylamine succinate and diphenhydramine

Jul 15, 2024
Doxylamine succinate is the only FDA Pregnancy Category A medication approved for nausea and vomiting of pregnancy. For breakthrough nausea and vomiting, diphenhydramine and promethazine can be additional therapeutic agents. Analysis of over 200,000 females, antihistamines have shown no congenital disabilities and no serious ….

Diphenhydramine is a type of medicine called an antihistamine. It is used in some allergy and sleep medicines. Diphenhydramine is a type of medicine called an antihistamine. It is ...Acetaminophen Dextromethorphan Hydrobromide Doxylamine Succinate Phenylephrine hydrochloride: Doxylamine succinate (6.25 mg/1) + Acetaminophen (325 mg/1) + Dextromethorphan hydrobromide monohydrate (10 mg/1) + Phenylephrine hydrochloride (5 mg/1) Capsule, liquid filled: Oral: Healthlife of Usa: 2017-07-07: 2017-07-07: USAnswer. If you had an adverse reaction to doxylamine, it is very possible you will have a similar experience with diphenhydramine. This is because both are first-generation antihistamines and are very similar to one another in terms of chemical structure and effect. They are both in the ethanolamine class of antihistamines, which are noted for ...H-E-B Nighttime Sleep-Aid Doxylamine Succinate Tablets. Ingredients. Ingredients Active Ingredients: In Each Tablet: Doxylamine Succinate (25 mg). Purpose: Nighttime Sleep-Aid. ... Add H-E-B Diphenhydramine Nighttime Sleep-Aid Softgels – 50 mg to list. $5.18 each ($0.16 / ct) H-E-B Diphenhydramine Nighttime Sleep-Aid Softgels – 50 mg. Aisle 32.Two Benadryl 25mg tablets would be equivalent to one Unisom SleepGel 50mg capsule. Unisom SleepTabs contain a drug called doxylamine. Doxylamine is a drug that is extremely similar to Benadryl. Both are “first-generation” antihistamines. Like Benadryl, it also commonly causes drowsiness, dizziness, dry mouth, constipation, urinary retention ...Before taking doxylamine and pyridoxine, tell your doctor and pharmacist if you are allergic to doxylamine (Unisom); pyridoxine (vitamin B6); other antihistamine medications including carboxamide (Arbinoxa), clemastine (Tavist), dimenhydrinate (Dramamine), diphenhydramine (Benadryl), and promethazine (Phenergan); any other medications; or any of the ingredients in doxylamine and pyridoxine ...The ALDH5A1 gene provides instructions for producing the succinic semialdehyde dehydrogenase enzyme. Learn about this gene and related health conditions. The ALDH5A1 gene provides ...Few times a week. Doxylamine succinate and Benadryl. I had a terrible bout of insomnia in January and February and took up to 5 59mg benadryl a night for weeks, same doxy alternating. I couldn't remember what i did a minute ago. I was dumb. I finally said im done with these forever. I knew the long term dementia issues, somehow the immediate ...Use of diphenhydramine over a long period of time can cause users to develop a tolerance to it, making increasingly larger doses necessary, warns Everyday Health. Common side effec...There wasn't a seat-back TV, but at least the Wi-Fi was lightning fast. Some offers mentioned below are no longer available. View the current offers here. Editor’s note: During the...An unusual or allergic reaction to doxylamine, other medications, foods, dyes, or preservatives; Pregnant or trying to get pregnant; Breast-feeding; How should I use this medication? Take this medication by mouth with a glass of water. Follow the directions on the package or prescription label. Take this medication 30 minutes before you go to bed.Benzodiazepines and Antihistamines Hey all. I have been switching off between clonazepam and lorazepam, all legit. prescribed. Doc has even spoke of alprazolam.Still trying to figure what works. Anyways, I read on a different thread that, to potentiate benzos alcohol should not be used, but instead antihistamines. I am currently …May 2, 2017 · Main outcome measure The proportion and characteristics of older adults taking at least one over-the-counter medication containing diphenhydramine or doxylamine. Results Of the 223 over-the-counter sleep medications listed by participants, 115 (52%) contained diphenhydramine or doxylamine. Using the Beers Criteria, we found that more than half ... 8 results for "doxylamine succinate" Results. Benadryl Allergy Relief Capsules - Fast-Acting Antihistamine Capsules - Starts to Work in 15 Minutes - 12 Capsules. 4.6 out of 5 stars 6,612. 1K+ bought in past month.Benzodiazepines and Antihistamines Hey all. I have been switching off between clonazepam and lorazepam, all legit. prescribed. Doc has even spoke of alprazolam.Still trying to figure what works. Anyways, I read on a different thread that, to potentiate benzos alcohol should not be used, but instead antihistamines. I am currently …INTRODUCTION. There is a greater burden of sleep difficulties (e.g., difficulty falling asleep, waking up too early) among older adults age 65 and older than any other age group in the United States (US). 1 Those experiencing sleep difficulties may seek medications to aid with their difficulties, either healthcare provider-administered psychotropic medication, 2 or over the counter (OTC ...Doxylamine succinate (Unisom SleepTabs) is an over-the-counter antihistamine that can be taken by adults and children ages 12 years and older who are having trouble falling asleep. It's a sleep aid that works by blocking certain chemicals (histamine) in your body. Doxylamine (Unisom SleepTabs) is taken by mouth once a day, about 30 minutes ...The ALDH5A1 gene provides instructions for producing the succinic semialdehyde dehydrogenase enzyme. Learn about this gene and related health conditions. The ALDH5A1 gene provides ...Mar 26, 2024 · View Source, doxylamine Trusted Source Medline Plus MedlinePlus is an online health information resource for patients and their families and friends. View Source. Indicated usage: Antihistamine sleep aids may be taken for short-term problems with falling or staying asleep; however, AASM does not recommend the use of these drugs for insomnia. 3 min read. Antihistamines are a class of drugs that help to treat the symptoms of various allergies. The main difference between first-generation and second-generation …Jul 16, 2020 · Phenylephrine hydrochloride, dextromethorphan hydrobromide, pseudoephedrine hydrochloride, guaifenesin, chlorpheniramine maleate, brompheniramine maleate, diphenhydramine hydrochloride, and doxylamine succinate were the common active ingredients, with all available OTC sinonasal remedies consisting of 1 or more of these ingredients. And yes, there are many case reports of that happening to people who took Doxylamine over Diphenhydramine. As for Doxylamine itself, it acts on similar receptors that Diphenhydramine does. One look at their chemical structures is all it takes for it to be obvious. Some people claim that Doxylamine is ever so slightly more euphoric somehow ...Oral. Doxylamine succinate 10 mg/pyridoxine hydrochloride 10 mg delayed-release tablets (Diclegis ): Initially, 2 tablets at bedtime. If symptoms the next day are adequately controlled, continue this dosage daily at bedtime. If symptoms persist into the afternoon of day 2, add 1 tablet in the morning on day 3.Benadryl or diphenhydramine (2.4–9.3 hours) Unisom or doxylamine (10 hours) Ambien, Ambien CR, or zolpidem (2.5 hours) Lunesta or eszopiclone (6 hours) Sonata or zaleplon (1 hour) Silenor or doxepin (15) Belsomra or suvorexant (12 hours) Trazodone (3–6 hours in first phase, 5–9 hours in second phase) Rozerem or ramelteon …Diphenhydramine or Doxylamine succinate? Just picked up both at the store today. Which one has a better chance of me falling asleep? I can’t see a doctor right now for heavy sleep meds, so over the counter it is right now. comments sorted by Best Top New Controversial Q&A Add a Comment Low ...Diphenhydramine is the active ingredient in Sleep Eze, Sominex, Nytol, Tylenol PM, and Unisom SleepGels; Doxylamine succinate. Doxylamine succinate is one of the most sedating antihistamines available over-the-counter (stronger than diphenhydramine). A single dose causes rapid and marked drowsiness in the vast majority of individuals.Few times a week. Doxylamine succinate and Benadryl. I had a terrible bout of insomnia in January and February and took up to 5 59mg benadryl a night for weeks, same doxy alternating. I couldn't remember what i did a minute ago. I was dumb. I finally said im done with these forever. I knew the long term dementia issues, somehow the immediate ...Doxylamine Succinate Overview. Diphenhydramine is used to relieve red, irritated, itchy, watery eyes; sneezing; and runny nose caused by hay fever, allergies, or the common cold. Diphenhydramine is also used to relieve cough caused by minor throat or airway irritation. Diphenhydramine is also used to prevent and treat motion sickness, …Doxylamine succinate is the only FDA Pregnancy Category A medication approved for nausea and vomiting of pregnancy. For breakthrough nausea and vomiting, diphenhydramine and promethazine can be additional therapeutic agents. Analysis of over 200,000 females, antihistamines have shown no congenital disabilities and no serious …Doxylamine succinate is the only FDA Pregnancy Category A medication approved for nausea and vomiting of pregnancy. For breakthrough nausea and vomiting, diphenhydramine and promethazine can be additional therapeutic agents. Analysis of over 200,000 females, antihistamines have shown no congenital disabilities and no serious …It is based on doxylamine succinate and diphenhydramine hydrochloride (the active ingredients of Doxylamine succinate and Benadryl, respectively), and Doxylamine succinate and Benadryl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.Jan 6, 2022 ... Diphenhydramine HCl 25-50 mg at bedtime – Diphenhydramine is often used for allergies but can also be used as needed for sleep. Morning ...Before taking doxylamine and pyridoxine, tell your doctor and pharmacist if you are allergic to doxylamine (Unisom); pyridoxine (vitamin B6); other antihistamine medications including carboxamide (Arbinoxa), clemastine (Tavist), dimenhydrinate (Dramamine), diphenhydramine (Benadryl), and promethazine (Phenergan); any other medications; or any of the ingredients in doxylamine and pyridoxine ...(a) Diphenhydramine hydrochloride. (b) Diphenhydramine citrate. Part C—Labeling § M010.50 Labeling of nighttime sleep-aid drug products (a) Statement of identity. The labeling of the product contains the established name of the drug, if any, and identifies the product as a "nighttime sleep-aid." (b) Indications.View Source, doxylamine Trusted Source Medline Plus MedlinePlus is an online health information resource for patients and their families and friends. View Source. Indicated usage: Antihistamine sleep aids may be taken for short-term problems with falling or staying asleep; however, AASM does not recommend the use of these drugs for insomnia.Two Benadryl 25mg tablets would be equivalent to one Unisom SleepGel 50mg capsule. Unisom SleepTabs contain a drug called doxylamine. Doxylamine is a drug that is extremely similar to Benadryl. Both are “first-generation” antihistamines. Like Benadryl, it also commonly causes drowsiness, dizziness, dry mouth, constipation, …little or no urinating. Common side effects of doxylamine may include: blurred vision; dry mouth, nose, or throat; constipation; or. mild dizziness or drowsiness. Side effects such as dry mouth, constipation, and confusion may be more likely in older adults. This is not a complete list of side effects and others may occur.Is diphenhydramine hydrochloride and doxylamine succinate ok together? Caution Required: Both drugs have similar "mechanisms of action." therefore, the effects they produce are "additive" and, in theory, can pile up to create more effects than would be predicted if each drug were taken by itself...Almost as if 1+1=3! both drugs produce sedation ...Few times a week. Doxylamine succinate and Benadryl. I had a terrible bout of insomnia in January and February and took up to 5 59mg benadryl a night for weeks, same doxy alternating. I couldn't remember what i did a minute ago. I was dumb. I finally said im done with these forever. I knew the long term dementia issues, somehow the immediate ...President Donald Trump has suggested adding a border tax to pay for border wall. That could increase new car prices by $2,500, on average. By clicking "TRY IT", I agree to receive ...To investigate the level of evidence supporting the use of common over-the-counter (OTC) agents (diphenhydramine, doxylamine, melatonin, and valerian) for occasional …Prescribed for Insomnia, Allergic Rhinitis, Allergies, Conjunctivitis - Allergic, Nasal Congestion, Rhinorrhea, Upper Respiratory Tract Infection. doxylamine may also be …Both doxylamine (Unisom) and diphenhydramine (Benadryl, ZzzQuil) can be used for short-term sleep problems for up to 2 weeks. They work similarly and they have similar side effects. Doxylamine stays in your system longer than diphenhydramine. So it may be …Doxylamine succinate, an ethanolamine-based antihistamine, shares the actions and uses of other antihistamines. Because of its sedative effect, doxylamine medicinal products (alone or in combination with other drugs) have been authorized for more than 50 years with an appropriate extent of use for short-term management of …Nytol, Sominex, and Unisom (the blue capsule form), for example, contain 25 to 50 milligrams (mg) of the antihistamine diphenhydramine per pill. Other over-the-counter sleep medications, such as Unisom SleepTabs, contain 25 mg per pill of an antihistamine called doxylamine succinate.Doxylamine causes more drowsiness than diphenhydramine. It is as effective as diphenhydramine, but the duration of effect is longer, for up to eight hours. …Doxylamine is an antihistamine of the ethanolamine class. It is used primarily as a sleep-inducing agent. Only a few reports can be found in the literature about lethal intoxications with doxylamine, but many with combined intoxications. Doxylamine is, aside from diphenhydramine, the only chemically defined active ingredient in some sleeping ...Doxylamine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Acetaminophen, dextromethorphan, and doxylamine is a combination medicine used to treat headache, fever, body aches, cough, runny nose, sneezing, and sore throat ...Phenylephrine hydrochloride, dextromethorphan hydrobromide, pseudoephedrine hydrochloride, guaifenesin, chlorpheniramine maleate, brompheniramine maleate, diphenhydramine hydrochloride, and doxylamine succinate were the common active ingredients, with all available OTC sinonasal remedies consisting of 1 or more of …Google, Microsoft and other blue-chip big tech companies are racing to integrate AI language tools like the popular ChatGPT into their search engines. Jump to ChatGPT's red-hot ris... Doxylamine Interactions. There are 311 drugs known to interact with doxylamine, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 18 are major, 292 are moderate, and 1 is minor. The SDHD gene provides instructions for making one of four subunits of the succinate dehydrogenase (SDH) enzyme. Learn about this gene and related health conditions. The SDHD gene ...Introduction. Doxylamine succinate, an ethanolamine-based antihistamine, shares the actions and uses of other antihistamines. Because of its sedative effect, doxylamine medicinal products (alone or in combination with other drugs) have been authorized for more than 50 years with an appropriate extent of use for short-term management of insomnia [1–5].doxylamine food. Applies to: Sleep Aid (doxylamine) Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with doxylamine.Doxylamine succinate 25 mg. Unisom® SleepTabs® contain doxylamine succinate, a non-habit-forming antihistamine that makes you sleepy by blocking the effects of histamine in the body, which helps you fall asleep fast and sleep through the night. SleepTabs® are FDA approved, clinically tested, and proven effective. All Ingredients.Doxylamine and pyridoxine combination is used to treat nausea and vomiting in pregnant women (also called morning sickness) whose symptoms have not been relieved by other treatments. This medicine is a combination of an antihistamine and vitamin B6. This medicine is available only with your doctor's prescription.Podcast episode answering schizophrenia questions like “What is having a hallucination like?” and “Why won’t my loved one get help?” Since May is Mental Health Awareness Month, our...A plant called “the scourge of the South” has a new strike against it. Recent research shows that the impact of the invasive species in question, kudzu, is more troublesome than ha...Only rarely are there simple answers to tax questions, and the rules associated with dependent deductions are some of the most complicated of all. It might be possible to claim you...Oct 6, 2015 · Dec 10, 2016. from U.S.A. My reptile finds that doxylamine works with dph in perfect synergy as if it's only DPH when using them to go to sleep. Doxlamine has a lower potency for many people, and a higher potency for some, but the consensus is that it knocks one out much more effectively than DPH. Many also report there is a more intense ... Doxylamine and diphenhydramine are Food and Drug Administration (FDA) approved antihistamines used to treat insomnia, motion sickness, hay fever, and common cold symptoms, among other uses. As commonly used medications, doxylamine and diphenhydramine, administered to adults and children, are available in generic and …Diphenhydramine (Benadryl, Nytol, Sominex) Doxylamine (Vicks NyQuil, Tylenol Cold and Cough Nighttime) These antihistamines start to take effect in about 30 to 60 minutes and last for four to six ...The type of drug taken also mattered. People who were on a long-acting benzodiazepine like diazepam (Valium) or flurazepam (Dalmane) were at greater risk than those on a short-acting one like triazolam (Halcion), lorazepam (Ativan), alprazolam (Xanax), or temazepam (Restoril). Why these drugs have a stronger effect in older people.Participants taking at least one diphenhydramine or doxylamine containing medication were less likely to be aware of any safety risks in taking over-the-counter sleep medications than participants not taking these products (38 vs 49%, p = 0.016). Conclusion A majority of older adults in a limited sample from the United States taking an over-the ...The study found a 50 percent increased risk of dementia among people who used a strong anticholinergic drug daily for about three years within that 10-year period. The association was stronger for ...Here are monthly recommended household budget percentages for each category that will help you create a budget that works. Home Money Management One of the best ways to be success...Diuretics cause your body to release more urine. Avoid drinks that may have a diuretic effect. These include: alcohol. coffee. soda. other caffeinated beverages. Avoiding or reducing intake of ...Jan 29, 2019 · Always check the labels on substances such as these, as sometimes diphenhydramine may be combined with other medications like non-steroidal anti-inflammatories (ibuprofen or naproxen) that can cause stomach ulcers and kidney injury. Doxylamine is an antihistamine very similar to diphenhydramine with similar concerns. It is not regularly used in ... urinary retention. Severe side effects can include: hives. a skin rash. difficulty breathing or swallowing. swelling in the face, mouth, or throat. delirium. Although rare, long-term use of non ...Diphenhydramine (Benadryl, Nytol, Sominex) Doxylamine (Vicks NyQuil, Tylenol Cold and Cough Nighttime) These antihistamines start to take effect in about 30 to 60 minutes and last for four to six ...urinary retention. Severe side effects can include: hives. a skin rash. difficulty breathing or swallowing. swelling in the face, mouth, or throat. delirium. Although rare, long-term use of non ...A report published in JAMA Internal Medicine several years ago highlighted a link between long-term use of anticholinergic medications like Benadryl and dementia. While this study and other observational studies have also found this association, it doesn't prove that these drugs cause dementia.Doxylamine and pyridoxine side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Common side effects of doxylamine and pyridoxine may include: drowsiness. This is not a complete list of side effects and others may occur.The type of drug taken also mattered. People who were on a long-acting benzodiazepine like diazepam (Valium) or flurazepam (Dalmane) were at greater risk than those on a short-acting one like …Doxylamine succinate, an oral first-generation H1-antihistamine drug is commonly used in sleep-inducing OTC mediations. A 69-year-old woman was admitted to an emergency department with a 1-day history of worsening drowsiness and confusion following ingestion of 16 tablets of 25 mg of doxylamine 48 h previously due to her recently exacerbated ...Drugs & Medications. Doxylamine Succinate Tablet - Uses, Side Effects, and More. Common Brand (S): Unisom Sleep Aid. Generic Name (S): doxylamine succinate. …

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That Mar 26, 2024 · Like diphenhydramine, doxylamine – also known as doxylamine succinate – is a first-generation antihistamine that can produce sedative effects. Doxylamine can serve as a short-term treatment for insomnia Trusted Source Medline Plus MedlinePlus is an online health information resource for patients and their families and friends. HealthA2Z Sleep Aid, Diphenhydramine Softgels, 50mg, Supports Deeper, Restful Sleeping, Non Habit-Forming (250 Counts) ... Kirkland Signature Sleep Aid Tablets active ingredient is Doxylamine Succinate 25mg, an antihistamine, that maybe used as a sleep aid by adults and children 12 years and older. Kirkland Signature Sleep Aid Tablets …Applies to: Zoloft (sertraline) and doxylamine. Using sertraline together with doxylamine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of ...

How Both doxylamine succinate and Diphenhydramine belong to the antihistamine group of medicines. Histamine is a chemical neurotransmitter released in the body in response to …Is it safe to take diphenhydramine and dextromethorphan together? A doctor has provided 1 answer. Dr. John Chiu answered. Specializes in Allergy and Immunology. Yes but: There may be some additive sedating effect from both. So be sure that you know how alert you feel before you drive. Answered 4/17/2017.The FDA has approved exactly three medications for use as OTC (over the counter) sleep aids: diphenhydramine hydrochloride, doxylamine succinate, and diphenhydramine citrate. All three of these are antihistamines and drowsiness is a side effect. Diphenhydramine Hydrochloride FDA approved for use as a sleep aid in 1989.Is diphenhydramine hydrochloride and doxylamine succinate ok together? Caution Required: Both drugs have similar "mechanisms of action." therefore, the effects they produce are "additive" and, in theory, can pile up to create more effects than would be predicted if each drug were taken by itself...Almost as if 1+1=3! both drugs produce sedation ...doxylamine food. Applies to: Sleep Aid (doxylamine) Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with doxylamine.

When Your doctor may request neuroimaging to screen mental or physical health. But what are the different types of brain scans and what could they show? Many brain imaging techniques ar...The characteristics of doxylamine are similar to those of diphenhydramine. It is generally used for insomnia in the same dosage range (25 to 50 mg) and also has a T1/2 of 10 to 12 hours. Doxylamine has a slightly faster absorption with a T max of 1.5 to 2.5 hours. 3 The primary elimination of doxylamine occurs through the CYP2D6, CYP1A2, and ...If you’re taking Unisom as a sleep aid, the recommended adult dosage is one 25-milligram (mg) tablet taken 30 minutes before bedtime. During pregnancy, it’s generally considered safe to take the typical adult dose. If prescribed Diclegis, you would take two tablets at bedtime. Each tablet contains 10 mg of doxylamine and 10 mg of pyridoxine ...…

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culver's clare mi 3 min read. Antihistamines are a class of drugs that help to treat the symptoms of various allergies. The main difference between first-generation and second-generation …View Source, doxylamine Trusted Source Medline Plus MedlinePlus is an online health information resource for patients and their families and friends. View Source. Indicated … carmike cullmancarl haviland Before taking doxylamine and pyridoxine, tell your doctor and pharmacist if you are allergic to doxylamine (Unisom); pyridoxine (vitamin B6); other antihistamine medications including carboxamide (Arbinoxa), clemastine (Tavist), dimenhydrinate (Dramamine), diphenhydramine (Benadryl), and promethazine (Phenergan); any other medications; or any of the ingredients in doxylamine and pyridoxine ...Few times a week. Doxylamine succinate and Benadryl. I had a terrible bout of insomnia in January and February and took up to 5 59mg benadryl a night for weeks, same doxy alternating. I couldn't remember what i did a minute ago. I was dumb. I finally said im done with these forever. I knew the long term dementia issues, somehow the immediate ... flowey fightwalmart remote data entry jobs2014 chevy cruze oil filter The US Food and Drug Administration (FDA) included diphenhydramine hydrochloride (up to 50 mg) and diphenhydramine citrate (up to 76 mg) as safe and effective nighttime sleep aids as part of the FDA Final Drug Monograph for OTC Use. 22 Doxylamine succinate (up to 25 mg) is not yet included in this monograph (on the basis of insufficient ... arizonapackages Anyone know the difference between Diphenhydramine HCL and Doxylamine Succinate in terms of effectiveness for insomnia, as well as side effects and long term use. Both seem effective for me but I suffer from a lot of medical conditions and don't want to make them worse.Benzodiazepines and Antihistamines Hey all. I have been switching off between clonazepam and lorazepam, all legit. prescribed. Doc has even spoke of alprazolam.Still trying to figure what works. Anyways, I read on a different thread that, to potentiate benzos alcohol should not be used, but instead antihistamines. I am currently … berks county cysbaptist eastpoint louisville kentuckyjerry seiner kia salt lake reviews Diphenhydramine (Benadryl, Advil PM, others). Doxylamine (NyQuil Cold & Flu, Nighttime Cold & Flu Relief, others). Chlorpheniramine (Chlor-Trimeton, Alka-Seltzer Plus Cold Medicine, others). Antihistamines that make you sleepy can be useful as a sleep aid once in a while. But tolerance to the effects of these antihistamines develops quickly.In patients older than 12 years of age: Nyquil™ (doxylamine succinate), Tavist (clemastine fumarate), chlorpheniramine maleate or Benadryl® (diphenhydramine) may help relieve symptoms, although these may cause sleepiness. Chlorpheniramine maleate is the least sedating of the products listed above. Nasal congestion